During the ages of middle adulthood, from 30 to 60, Low T is typically manifested in symptoms that can include low interest in sex; low semen volume; difficulty getting and maintain erections; decreased muscle strength; hot flashes; increased body fat; longer recovery time from exercise; reduced energy and stamina; lack of mental concentration; and mood changes that are often exhibited as irritability, anxiety or depression. Treatment reverses these types of symptoms and replenishes a middle-aged male’s vitality and sexual virility, helps to improve his physique, sharpens his mental focus and restores his sense of emotional wellbeing.
It is suggested that bioavailable testosterone represents the fraction of circulating testosterone that readily enters cells and better reflects the bioactivity of testosterone than does the simple measurement of serum total testosterone. Also, varying levels of SHBG can result in inaccurate measurements of bioavailable testosterone. Decreased SHBG levels can be seen in obesity, hypothyroidism , androgen use, and nephritic syndrome (a form of kidney disease ). Increased levels are seen in cirrhosis , hyperthyroidism , and estrogen use. In these situations, measurement of free testosterone may be more useful.
A month after my initial visit, I was back in my endocrinologist’s office for the results of a follow-up blood test. Put off by the prospect of infertility, I’d been very reluctant to go the TRT route, and opted instead for a clomiphene citrate, or Clomid. Designed to stimulate ovulation in women, the pills have also proven effective at raising T levels in men with secondary hypogonadism—that is, men whose difficulty producing testosterone stems from problems in the hypothalamus or the pituitary gland. In many cases, Clomid can prod the body into upping its production of testosterone.