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Patients with an established diagnosis of diabetes mellitus who are started on atypical antipsychotics, including Risperdal ® , should be monitored regularly for worsening of glucose control. Patients with risk factors for diabetes mellitus (., obesity, family history of diabetes) who are starting treatment with atypical antipsychotics, including Risperdal ® , should undergo fasting blood glucose testing at the beginning of treatment and periodically during treatment. Any patient treated with atypical antipsychotics, including Risperdal ® , should be monitored for symptoms of hyperglycemia including polydipsia, polyuria, polyphagia, and weakness. Patients who develop symptoms of hyperglycemia during treatment with atypical antipsychotics, including Risperdal ® , should undergo fasting blood glucose testing. In some cases, hyperglycemia has resolved when the atypical antipsychotic, including Risperdal ® , was discontinued; however, some patients required continuation of anti-diabetic treatment despite discontinuation of Risperdal ® .

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