Exogenous testosterone definition

Testosterone patches can be either scrotal or non-scrotal and are also known to be effective in increasing the body’s T-levels. The downside to using this however is that it tends to irritate the skin. Testosterone gels are known to be significantly absorbed by the skin and have a near-instant absorption rate which lasts throughout the day. And there’s also the buccal testosterone which is known to produce even better results than the patches when applied to the gums. The side effects of that however often include bitter taste in the mouth and some irritation to the gums.

Fluid and electrolyte disturbances: Retention of sodium, chloride, water, potassium, calcium, and inorganic phosphates.
 
Gastrointestinal: Nausea, cholestatic jaundice, alterations in liver function tests, rarely hepatocellular neoplasms and peliosis hepatis (see WARNINGS ).
 
Hematologic: Suppression of clotting factors II, V, VII, and X, bleeding in patients on concomitant anticoagulant therapy, and polycythemia.
 
Nervous system: Increased or decreased libido, headache, anxiety, depression, and generalized paresthesia.
 
Allergic: Hypersensitivity, including skin manifestations and anaphylactoid reactions.
 
Vascular Disorders: venous thromboembolism

Miscellaneous: Inflammation and pain at the site of intramuscular injection.

-->

  • Learn ▾
    • Lifestyle
      • Exercise & Fitness
      • Food & Nutrition
      • Sleep & Wellness
    • Aging
      • Aging & Bodily Changes
      • Testosterone
      • Human Growth Hormone
    • Men’s Health
      • General Health Topics
      • Health Numbers
  • Engage ▾
    • Workout Routines
      • Muscle Growth
      • Muscle Endurance
      • Strength & Endurance
    • Exercise Videos
      • Resistance
      • Lower Back Care
      • Abdominal
      • Stretching
    • My Health
      • BMI Calculator for Men
      • BMR Calculator for Men
      • Waist to Height Ratio Calculator
      • Health Check
  • Testosterone

*Information on this site is provided for informational purposes only and is not meant to be a substitute for the advice of your healthcare provider or any other medical professional. The statements on this website have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Each user's experience is unique; results may vary. Apple, iPhone, iPad, and the Apple logo are trademarks of Apple Inc., registered in the . and other countries. App Store is a service mark of Apple Inc., registered in the . and other countries.

A recent case of a 51 year old male with an interest in testosterone replacement illustrates the benefits of the multi-parametric prostate MRI scan. Noting a PSA value of only ng/ml; the digital rectal exam (DRE) identified an area of interest on the left side, albeit, it was not definitive for prostate cancer. Neither the gray scale ultrasound nor Color Flow Doppler ultrasound evaluation suggested any specific abnormality consistent with the area of interest previously identified on DRE. An MRI scan was suggested as the next best step in the evaluation. The scan isolated a region of interest on the left side at the Apex to Middle portion of the prostate gland concordant with the findings on the DRE.  Based upon the findings of the MRI scan, a targeted biopsy with 6 needle cores was recommended and implemented. An Antiandrogen was initiated pre-biopsy to mitigate against “needle tracking”. Specifically, an Antiandrogen selectively blocks the receptor on the prostate cell from attracting testosterone as it exits the capsule, thereby, disabling the cells in preparation for cell death or apoptosis. The Pathology evaluation revealed a grade of cancer that was amenable to being treated conservatively or focally. In this case, the failure to use a MRI scan would have exposed this patient to the possibility of missing the cancer altogether; associated with sampling bias, a very real possibility for needle tracking (assuming cancer was found), or worse yet, the go ahead to supplement with testosterone, when in fact, the cancer was missed. Using  testosterone in this scenario would have stimulated cancer cells to grow wildly, while causing the PSA to spike abnormally, thereby, making the diagnosis of prostate cancer – a potentially uncontrollable clinical event, albeit, avoidable. Given the expertise of a Urolologic consultation, this case turned out well. The patient is now contemplating a focal treatment with high intensity focused ultrasound with a plan to supplement with testosterone once his cancer has been cured. An inability to document the resolution of prostate cancer by a repeat MRI scan and/or a stable PSA post-operatively will preclude this patient from using testosterone replacement therapy.

All bets are off the table when high-dose testosterone and its many metabolites are used illegally, such as with anabolic steroid abuse. Strokes, embolisms, and cardiovascular disease are all more likely, as is sudden death, and liver and kidney disease. 44 In women, acne, irreversible deepening of the voice, baldness, increased facial hair, enlarged sex organs, breast reduction, depression, and infertility have all been reported. In adult men that abuse anabolic steroids, acne, baldness, permanent infertility, gynecomastia, loss of libido, erectile dysfunction, testicle shrinkage, and profuse sweating are all reported side effects. Increased testicular cancer hasn't been reported, though. 45,46

Exogenous testosterone definition

exogenous testosterone definition

*Information on this site is provided for informational purposes only and is not meant to be a substitute for the advice of your healthcare provider or any other medical professional. The statements on this website have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Each user's experience is unique; results may vary. Apple, iPhone, iPad, and the Apple logo are trademarks of Apple Inc., registered in the . and other countries. App Store is a service mark of Apple Inc., registered in the . and other countries.

Media:

exogenous testosterone definitionexogenous testosterone definitionexogenous testosterone definitionexogenous testosterone definitionexogenous testosterone definition