Because the ultimate goal of a steroid cycle is to increase strength and muscle size, the associated spike in estrogen which accompanies steroids such as Testosterone is considered undesirable. In order to disassociate the two effects, two classes of drug are used. Medications such as Nolvadex or Clomid target the estrogen receptors. They make it more difficult for the estrogen to exert it’s influence within the body thus allowing the testosterone to act more freely. The second class is aromatase inhibitors such as Femara. They target the aromatase enzyme itself in order to prevent the production of estrogen in the first place. Sometimes, it’s not always clear which option you should go with or even what the differences are between the two. Lets clear that up a little.
Interestingly, estrogen dominance can lead to the symptoms of thyroid problems , one of which is hair loss!
What happens is that the liver creates too much thyroid binding globulin (TBG) when estrogen levels are high. TBG binds the thyroid hormones in the blood, meaning that they can't be absorbed as needed by the cells in the body that use them to support the body's metabolism.
The difficulty is that standard blood tests for thyroid conditions don't show up the problem.
The AMOUNT of thyroid hormone in the blood is just as it should be - but the hormone is being bound by the TBG.
The result is that the symptoms of thyroid problems start to appear.
TBG can. however, be detected with a blood test , so it's important to bear this in mind and ask to be tested if you feel this may be the problem you're experiencing.
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